Line a baking sheet with aluminum foil and place the salmon fillet skin-side down on top.
In a mixing bowl, combine melted butter and minced garlic, then brush half over the salmon.
In another bowl, mix together brown sugar, Italian seasoning, paprika, garlic powder, salt, and black pepper. Sprinkle this spice mix evenly over the salmon.
Drizzle any remaining garlic butter over the seasoned fillet.
Bake for 15-22 minutes until the internal temperature reaches between 145°F to 150°F.
Allow the salmon to rest for about 5 minutes before serving.